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Gastric Mucosal Lesions and NSAIDs

March 17, 2011 by Dr. Marc Darrow, M.D.  
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imagesCAWV2N3G Gastric Mucosal Lesions and NSAIDsResearchers writing in Journal of Orthopaedic Science studied endoscopic examinations to determine the status of gastric mucosal lesions in patients receiving long-term non-steroidal anti-inflammatory drugs (NSAIDS) therapy.

Yajima H, Yamao J, Fukui H, Takakura Y. J Orthop Sci. 2007 Jul;12(4):341-6. Epub 2007 Aug 2. Up-to-date information on gastric mucosal lesions from long-term NSAID therapy in orthopedic outpatients: a study using logistic regression analysis.

The researchers concluded: Diclofenac can cause gastric mucosal lesions, including ulcers, more easily than other NSAIDs. H. pylori infection is a high-risk factor for ulcers in patients receiving long-term NSAIDs therapy. In NSAID-treated patients, subjective symptoms are not grounds for a diagnosis of gastric mucosal lesions, especially ulcers.

Written by Dr. Marc Darrow, M.D.

To Learn More Call 1-800-REHAB10. As one of the leading prolotherapy practicioners, Dr. Marc Darrow, M.D. developed the Prolotherapy Institute to educate patients, their caregivers and the medical community about the benefits of Prolotherapy. Dr. Marc Darrow is a Board Certified Physiatrist specializing in Physical Medicine and Rehabilitation. He is also an Assistant Clinical Professor at University of California School of Medicine, Los Angeles, where he trained, and teaches Prolotherapy to the doctors in their residency training.

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